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Results for "

Entamoeba histolytica

" in MedChemExpress (MCE) Product Catalog:

18

阻害剤およびアゴニスト

6

天然物

製品番号 製品名 Target 研究分野 構造式
  • HY-B0318
    Metronidazole
    60+ Cited Publications

    		 Environmental Pollutants Antibiotic Bacterial Apoptosis Parasite Infection Inflammation/Immunology Cancer
    Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections .
    Metronidazole
  • HY-N2263
    Skimmin
    1 Publications Verification

    Umbelliferone glucoside

    		 Interleukin Related TGF-β Receptor TNF Receptor Parasite Inflammation/Immunology
    Skimmin (Umbelliferone glucoside) is a major pharmacologically active and orally active molecule present in Hydrangea paniculata, a medical herb used in traditional Chinese medicine as an anti-inflammatory agent. Skimmin has renal protective activity. Skimmin can improve creatinine clearance, and reduce plasma creatinine, and kidney injuries. Skimmin has good anti-amoebic activity against the HM1:IMMS strain of Entamoeba histolytica. Skimmin has anti-cancer and neuroprotective activities. Skimmin reduces cardiac fibrosis as well as decreasing TNF-α, IL-6, IL1β, and TGFβ1 in cardiac tissues. Skimmin can be studied in research for diabetes and diabetes-related diseases .
    Skimmin
  • HY-15537
    Tilbroquinol
    1 Publications Verification

    		 Parasite Bacterial Infection
    Tilbroquinol is an orally active halogenated hydroxyquinoline antiprotozoal agent, mainly used for anti-amoebic infections . Tilbroquinol targets intestinal protozoa and Entamoeba histolytica to eliminate parasites in the intestinal lumen. Tilbroquinol can be used in research related to intestinal infections, intestinal amoebiasis and hepatic amoebiasis .
    Tilbroquinol
  • HY-121241
    Dehydroemetine

    		Parasite Infection
    Dehydroemetine is an orally active antiparasitic agent. Dehydroemetine can inhibit parasites such as Entamoeba histolytica, and it can also be used in the research of parasitic diseases like visceral leishmaniasis .
    Dehydroemetine
  • HY-119972
    Diloxanide

    		Parasite Infection
    Diloxanide is an anti-protozoal agent and can be used for the research of asymptomatic-intestinal amebiasis caused by Entamoeba histolytica or some other protozoal infections. Diloxanide is an active luminal amebicide and hydrolyzed in the gastrointestinal tract from its proagent Diloxanide furoate (HY-B1147) .
    Diloxanide
  • HY-B1147
    Diloxanide furoate
    1 Publications Verification

    		 Parasite Infection
    Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .
    Diloxanide furoate
  • HY-B0318R
    Metronidazole (Standard)

    		Reference Standards Bacterial Parasite Apoptosis Antibiotic Infection Inflammation/Immunology Cancer
    Metronidazole (Standard) is the analytical standard of Metronidazole. This product is intended for research and analytical applications. Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections .
    Metronidazole (Standard)
  • HY-B0318A
    Metronidazole hydrochloride
    Maximum Cited Publications
    65 Publications Verification

    SC 326421

    		 Antibiotic Bacterial Parasite Apoptosis Infection Inflammation/Immunology Cancer
    Metronidazole hydrochloride (SC 326421) is an orally active nitroimidazole antibiotic, can be used to research anaerobic infections. Metronidazole hydrochloride can cross blood brain barrier and results inflammation and skeletal muscle contraction under long-term application .
    Metronidazole hydrochloride
  • HY-B0956A
    Paromomycin

    Aminosidine

    		 Bacterial Parasite Endogenous Metabolite Infection
    Paromomycin (Aminosidine) is an orally active broad-spectrum aminoglycoside aminocyclitol. Paromomycin is produced by Streptomyces riomosus var. Paromomycinus. Paromomycin binding induces local conformational changes in the 16S rRNA A-site. Paromomycin exhibits inhibitory activity against C. parvum. Paromomycin can be used in research related to leishmaniasis, amoebiasis and cryptosporidiosis .
    Paromomycin
  • HY-N10471
    F3226-1387

    		Parasite Endogenous Metabolite Infection
    F3226-1387 is a potent Entamoeba histolytica O-acetylserine sulfhydrylase EhOASS3 inhibitor with an IC50 value of 38 μM. F3226-1387 can suppress the growth of the amoeba .
    F3226-1387
  • HY-W098008
    Fenbendazole analog-1

    		Parasite Microtubule/Tubulin Infection
    Fenbendazole analog-1 (compound 9) is a 2-methoxycarbonylamino-derived antiparasitic compound and inhibits rat brain tubulin polymerization. Fenbendazole analog-1 inhibits the growth of the protozoa Giardia lamblia, Entamoeba histolytica, and the worm Trichinella spiralis .
    Fenbendazole analog-1
  • HY-101590A
    Symetine dihydrochloride

    L 16726 dihydrochloride

    		 Parasite Infection
    Symetine dihydrochloride (L 16726 dihydrochloride) is the dihydrochloride form of Symetine (HY-101590). Symetine dihydrochloride exhibits antiprotozoal activity aginst Entamoeba histolytica, and ameliorates the amebic liver abscess in guinea pig model .
    Symetine dihydrochloride
  • HY-B1147R
    Diloxanide furoate (Standard)

    		Reference Standards Parasite Infection
    Diloxanide furoate (Standard) is the analytical standard of Diloxanide furoate. This product is intended for research and analytical applications. Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .
    Diloxanide furoate (Standard)
  • HY-181644
    NS-181

    		MetAP Infection
    NS-181 is an orally active MetAP2 inhibitor and antiamebic agent with oral effectiveness.NS-181 functionally inhibits methionine aminopeptidase 2, a protein critical for Entamoeba histolytica proliferation. NS-181 exerts antiamebic activity against Entamoeba histolytica, leading to resolution of amebic liver abscess. NS-181 can be used for the research of amebiasis .
    NS-181
  • HY-181643
    YOK24

    		MetAP Infection
    YOK24 is an orally active MetAP2 inhibitor and anti-amoebic agent. YOK24 binds covalently to MetAP2 and inhibits its peptidase activity, where MetAP2 is a protein essential for the proliferation of *Entamoeba histolytica*. YOK24 can be used in the research of amoebiasis .
    YOK24
  • HY-W779743
    NE58043

    		Drug Derivative Infection Cancer
    NE58043 (Compound 21) is a nitrogen-containing bisphosphonate compound. NE58043 has no significant inhibitory activity against Entamoeba histolytica and Plasmodium falciparum with IC50 > 200 μM. NE58043 shows a LD50 of 171 μM for human nasopharyngeal carcinoma KB cells. NE58043 can be used for the research of cancer and infection, such as nasopharyngeal carcinoma .
    NE58043
  • HY-N18080
    Parthenin

    		Parasite DNA Alkylator/Crosslinker Bacterial Infection Inflammation/Immunology Cancer
    Parthenin is a pseudoguaianolide-type sesquiterpene lactone present in Parthenium hysterophorus L. Parthenin induces chromosomal aberrations, mainly chromatid breaks, in human peripheral blood lymphocytes. Parthenin exhibits toxicity against Salmonella typhimurium and Escherichia coli strains, with reduced toxicity in the presence of a metabolic activation system (S9). Parthenin acts as an antifeedant against the 6th instar larvae of the tobacco cutworm (Spodoptera litura). Parthenin shows insecticidal activity against adult cowpea weevils (Callosobruchus maculatus). Parthenin inhibits seed germination and seedling growth of sicklepod (Cassia tora). Parthenin possesses nematicidal activity against the 2nd instar larvae of the southern root-knot nematode (Meloidogyne incognita). Parthenin serves as a research agent for studies related to cancer, malaria, amoebiasis, inflammatory diseases, and bacterial infections .
    Parthenin
  • HY-119475
    Satranidazole

    		Bacterial Insecticide DNA/RNA Synthesis Infection
    Satranidazole is an orally active insecticide and antimicrobial agent with high electron affinity. Satranidazole forms reduced nitro intermediates, which interact with DNA, causing helix instability, strand breakage and release of thymidine derivatives. Satranidazole exhibits antitrichomonal activity against Trichomonas vaginalis and Trichomonas foetus, and antiamoebic activity in rodent models of hepatic amoebiasis and caecal amoebiasis. Satranidazole inhibits the replication of bacteriophage φX174 DNA. Satranidazole can be used in research related to caecal amoebiasis, trichomoniasis and anaerobic bacterial infections .
    Satranidazole

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