4914-30-1
4914-30-1
Chemical Structure
Dehydroemetine
- CAS No.: 4914-30-1
- Formula:C29H38N2O4
- Molecular Weight:478.62
IUPAC Name: (S)-2-(((R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-3-ethyl-9,10-dimethoxy-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline
InChIKey: XXLZPUYGHQWHRN-RPBOFIJWSA-N
SMILES: COC1=CC2=C(C=C1OC)CCN[C@@H]2CC3=C(CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3
Biological Activity: Dehydroemetine is an orally active antiparasitic agent. Dehydroemetine can inhibit parasites such as Entamoeba histolytica, and it can also be used in the research of parasitic diseases like visceral leishmaniasis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dehydroemetine | 99.90% | Dehydroemetine is an orally active antiparasitic agent. Dehydroemetine can inhibit parasites such as Entamoeba histolytica, and it can also be used in the research of parasitic diseases like visceral leishmaniasis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-167739(S,S)-Dehydroemetine -
Similarity Score 0.82
HY-123303NSC-134754 -
Similarity Score 0.68
HY-N4118Cephaeline -
Similarity Score 0.68
HY-N2076Cephaeline hydrochloride -
Similarity Score 0.67
HY-N2260Cephaeline dihydrochloride -
Similarity Score 0.67
HY-163685Bisobrin -
Similarity Score 0.60
HY-N0137Tetrahydropapaverine hydrochloride -
Similarity Score 0.60
HY-N0137A(R)-Tetrahydropapaverine hydrochloride -
Similarity Score 0.60
HY-N19280Psychotrine -
Explore the MedChemAI to find more analogs
References
- [1]. SALEM HH, et al. DEHYDROEMETINE IN ACUTE AMOEBIASIS. Trans R Soc Trop Med Hyg. 1964 Nov;58:539-44. [Content Brief]
- [2]. Salako LA. Pharmacodynamic effects of dehydroemetine. J Pharm Pharmacol. 1972 Jan;24(1):32-9. [Content Brief]
- [3]. Fouarge M, et al.Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis.J Microencapsul. 1989 Jan-Mar;6(1):29-34. [Content Brief]
