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Cat. No.: HY-N2076

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Cephaeline hydrochloride

(Synonyms: (-)-Cephaeline hydrochloride; NSC 32944 monohydrochloride)

2 Cited Publications

Customer Review

Based on 2 publication(s) in Google Scholar

Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections.

For research use only. We do not sell to patients.

CAS No.: 3738-70-3
Formula: C₂₈H₃₉ClN₂O₄
Molecular Weight:503.07

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Cephaeline hydrochloride Chemical Structure

CAS No.: 3738-70-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (2)
Purity & Documentation
References
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Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

EBOV

All Filovirus Isoforms :

Chemical Information

CAS No. 3738-70-3
Molecular Weight 503.07
Formula C₂₈H₃₉ClN₂O₄
SMILES

OC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC.[H]Cl
Synonyms

(-)-Cephaeline hydrochloride; NSC 32944 monohydrochloride
Structure Classification
- Alkaloids
- Isoquinoline Alkaloids
- Phenols
- Monophenols
Initial Source
- Plants
- other families
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

All Cell Proliferation/Viability AssayCell Migration/Invasion AssayWB

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Journal Impact Factor

J Cancer Res Clin Oncol

Prognostic value of amino acid metabolism-related gene expression in invasive breast carcinoma. [Abstract]

2023 Oct;149(13):11117-11133. PMID: 37340191

Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133. [Abstract]

MDA-MB-231 and MCF-7 cells were treated with different dose of Cephaeline (0.1, 0.5, 1, 5, 10 μM) and cell viability were calculated by Cell Counting Kit-8.

Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133. [Abstract]

Representative images of cell scratch-wound healing test taken by a microscope at × 100 magnification treated with Cephaeline (0.2, 0.4 μM).

Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133. [Abstract]

Representative western blots for PI3K/AKT signal pathway and HIF-1α under different doses of Cephaeline (0.1, 0.2, 0.3, 0.4, 0.5 μM).
Daru

Cephaeline promotes ferroptosis in breast cancer via p53/SLC7A11/GPX4 axis. [Abstract]

2026 Jun 19;34(2):38. PMID: 42319734

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529.

[2]. Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Cephaeline hydrochloride

2 Cited Publications

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (2)
Purity & Documentation
References

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1/16

Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133. [Abstract]

Customer Validation
MDA-MB-231 and MCF-7 cells were treated with different dose of Cephaeline (0.1, 0.5, 1, 5, 10 μM) and cell viability were calculated by Cell Counting Kit-8.
1/16

Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133. [Abstract]

Customer Validation
Representative images of cell scratch-wound healing test taken by a microscope at × 100 magnification treated with Cephaeline (0.2, 0.4 μM).
1/16

Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133. [Abstract]

Customer Validation
Representative western blots for PI3K/AKT signal pathway and HIF-1α under different doses of Cephaeline (0.1, 0.2, 0.3, 0.4, 0.5 μM).

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Cephaeline hydrochloride

High-Throughput Bioactive Compound Library

Publications Citing Use of MedChemExpress (MCE) Cephaeline hydrochloride

All Filovirus Isoforms

Biological Activity

Chemical Information

Publications (2)

Purity & Documentation

References

Calculators

Help & FAQs

Cephaeline hydrochloride

High-Throughput Bioactive Compound Library

Publications Citing Use of MedChemExpress (MCE) Cephaeline hydrochloride

All Filovirus Isoforms

Biological Activity

Chemical Information

Publications (2)

Purity & Documentation

References

Calculators

Help & FAQs

Cephaeline hydrochloride Related Classifications

HY-N2076 Related Classifications