2. Anti-infection
  3. Flavivirus Filovirus
  4. Cephaeline hydrochloride

Cephaeline hydrochloride  (Synonyms: (-)-Cephaeline hydrochloride; NSC 32944 monohydrochloride)

Cat. No.: HY-N2076
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Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections.

For research use only. We do not sell to patients.

CAS No. : 3738-70-3

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Customer Review

Based on 1 publication(s) in Google Scholar

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Top Publications Citing Use of Products

1 Publications Citing Use of MCE Cephaeline hydrochloride

Cell Proliferation/Viability Assay
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WB

    Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133.  [Abstract]

    MDA-MB-231 and MCF-7 cells were treated with different dose of Cephaeline (0.1, 0.5, 1, 5, 10 μM) and cell viability were calculated by Cell Counting Kit-8.

    Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133.  [Abstract]

    Representative images of cell scratch-wound healing test taken by a microscope at × 100 magnification treated with Cephaeline (0.2, 0.4 μM).

    Cephaeline hydrochloride purchased from MedChemExpress. Usage Cited in: J Cancer Res Clin Oncol. 2023 Oct;149(13):11117-11133.  [Abstract]

    Representative western blots for PI3K/AKT signal pathway and HIF-1α under different doses of Cephaeline (0.1, 0.2, 0.3, 0.4, 0.5 μM).

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    Description

    Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections[1][2].

    IC50 & Target

    EBOV

     

    Molecular Weight

    503.07

    Formula

    C28H39ClN2O4
    CAS No.
    SMILES

    OC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC.[H]Cl
    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Cephaeline hydrochloride Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Cephaeline3738-70-3(-)-Cephaeline NSC 32944 monohydrochlorideFlavivirusFilovirusphenolicalkaloidZikavirusEbolaInhibitorinhibitorinhibit

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