1 Result for "

F5446

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "F5446" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-150190
CAS No.: 2304465-89-0
Purity:  99.38%
Research Areas:  

Cancer

F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo .
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