1 Result for "

FBXW7-R465C

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FBXW7-R465C" in MCE Product Catalog:

Cat. No.: HY-173082
CAS No.: 2765058-89-5
Target:  

PROTACs FKBP

Research Areas:  

Cancer

10-SLF is an FKBP12 PROTAC degrader. 10-SLF covalently interacts with the cysteine residue of FBXW7 R465C, forms a ternary complex with FKBP12, and promotes FBXW7-R465C-dependent proteasomal degradation of FKBP12. 10-SLF can be used for the research of pancreatic cancer .
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