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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
FF2039
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "FF2039" in MCE Product Catalog:
Cat. No.: HY-172159
FF2039 (compound 1j) is a specific HDAC1, HDAC6, and HDAC isoforms of class I, IIa and IIb PROTAC degrader. FF2039 demonstrates s significant antiproliferative activity against both hematological and solid cancer cell lines, driven by cell cycle arrest and Apoptosis induction. FF2039 inhibits HDAC isoform of HDAC1, HDAC2, HDAC4 and HDAC6 with IC50s of 1.03, 2.15, 12.4 and 0.053 μM, respectively. FF2039 shows antiproliferative activity against different tumor entities of MM.1S, MDA-MB-231 and U-87MG with EC50s of 2.8, 28 and 30 μM, respectively. (Pink: PRMT5 ligand (HY-168864); Blue: E3 ligase ligand HY-W957284); Black: linker (HY-W881439); E3+linker (HY-172185 )) .
Cat. No.: HY-W957284
CAS No.: 2940939-13-7
Target:
Research Areas:
DCAF11 ligand 1 is the ligand for E3 ligase DCAF11 and can be used for PROTAC synthesis of FF2039 (HY-172159) .
Cat. No.: HY-W881439
CAS No.: 2703752-86-5
Target:
Research Areas:
1-(1,1-Dimethylethyl) tridecanedioate is a PROTAC Linker and can be used for PROTAC synthesis, such as
FF2039 (HY-172159) .
Cat. No.: HY-172185
Research Areas:
E3 Ligase Ligand-linker Conjugate 172 is the conjugate composed of an E3 ligase ligand and a linker, and can be used for synthesis of PROTAC degrader FF2039 (HY-172159) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
