2 Results for "

Fe dual chelator ligand

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Fe dual chelator ligand" in MCE Product Catalog:

Cat. No.: HY-P1997
CAS No.: 34787-28-5
Synonyms: DesFerrichrome; DFC; N-DesFerriFerrichrome
Target:  

JNK Apoptosis

Research Areas:  

Infection Cancer

Ferrichrome Iron-free (Desferrichrome; DFC; N-Desferriferrichrome) is the ligand form of iron-loaded Ferrichrome when it is not bound to Fe 3+. Ferrichrome Iron-free induces apoptosis in gastric cancer cells by activating the JNK-DDIT3 apoptotic axis. As an iron chelator, Ferrichrome Iron-free enables dual-modal imaging of HER2 via conjugation with SiR and Trastuzumab (HY-P9907). Ferrichrome Iron-free can be used in the research of gastric cancer and HER2-overexpressing cancers .
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Cat. No.: HY-170433
Target:  

Apoptosis Ferroptosis

Research Areas:  

Cancer

DefNEtTrp is a Fe dual chelator ligand, consisting of the Def and Trp moieties. DefNEtTrp exhibits potent and broad-spectrum antiproliferative and cell death behavior in cancer cell lines. DefNEtTrp induces both apoptosis and ferroptosis and has cytotoxicity with an IC50 value of 0.77 μM .
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