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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Fenton system
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Fenton system" in MCE Product Catalog:
Synonyms: 1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine) is a phosphatidylethanolamine phospholipid with a palmitoyl chain at sn-1 and a linoleoyl chain at sn-2, and an oxidation-prone substrate. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE undergoes glycation and subsequent oxidation via Fenton system, forming long-chain and short-chain products at C-7, C-8, C-9, C-12 of its sn-2 acyl chain and glycated polar head. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE’s glycated form oxidizes more quickly than non-glycated phosphatidylethanolamines and contributes to increased oxidative stress modifications. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE can be used for the research of drug delivery .
Cat. No.: HY-177483
Synonyms: Oxaliplatin-artesunate
Target:
Ferroptosis Mitochondrial Metabolism Glutathione Peroxidase Transferrin Receptor MMP Dihydroorotate Dehydrogenase
Research Areas:
OART (Oxaliplatin-artesunate) is a ferroptosis inducer. OART significantly inhibits tumor cell proliferation. OART induces cytoplasmic and mitochondrial LPO to promote tumor ferroptosis, via destroying glutathione-mediated ferroptosis defense system and enhancing iron-dependent Fenton reaction. OART enhances tumor immunogenicity, transforming tumor environment from immunosuppressive to immunosensitive. OART has strong tumor regression in tumor-bearing mouse models. OART can be used for cancer immunotherapy research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
