26662-95-3
Chemical Structure
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE
Synonym(s): 1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine
- CAS No.: 26662-95-3
- Formula:C39H74NO8P
- Molecular Weight:715.98
IUPAC Name: (2R)-1-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate
InChIKey: HBZNVZIRJWODIB-NHCUFCNUSA-N
SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(O[C@@H](COP(O)(OCCN)=O)COC(CCCCCCCCCCCCCCC)=O)=O
Biological Activity: 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine) is a phosphatidylethanolamine phospholipid with a palmitoyl chain at sn-1 and a linoleoyl chain at sn-2, and an oxidation-prone substrate. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE undergoes glycation and subsequent oxidation via Fenton system, forming long-chain and short-chain products at C-7, C-8, C-9, C-12 of its sn-2 acyl chain and glycated polar head. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE’s glycated form oxidizes more quickly than non-glycated phosphatidylethanolamines and contributes to increased oxidative stress modifications. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE can be used for the research of drug delivery[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE | 98.0% | 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine) is a phosphatidylethanolamine phospholipid with a palmitoyl chain at sn-1 and a linoleoyl chain at sn-2, and an oxidation-prone substrate. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE undergoes glycation and subsequent oxidation via Fenton system, forming long-chain and short-chain products at C-7, C-8, C-9, C-12 of its sn-2 acyl chain and glycated polar head. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE’s glycated form oxidizes more quickly than non-glycated phosphatidylethanolamines and contributes to increased oxidative stress modifications. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE can be used for the research of drug delivery. | ||||||||||||||||||||
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