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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Fis1
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Fis1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P10368
CAS No.: 1411976-18-5
Target:
Research Areas:
Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
1
1 Cited Publications
Target:
Research Areas:
nti-inflammatory agent 49 (compound SC9) is a quite potent and selective inhibitor of Drp1-Fis1 interaction and can reduce FIS1-mediated mitochondrial dysfunction. The IC50 of SC9 inhibiting GTPase in vitro is 270 nM [1].
Cat. No.: HY-P2280
CAS No.: 2247617-97-4
Synonyms: P110
Target:
Research Areas:
Cat. No.: HY-172942
CAS No.: 2629218-24-0
Research Areas:
Cardiovascular Disease Infection Neurological Disease Cancer
SP11 is a mitochondrial fission protein 1 (Fis1) inhibitor with an IC50 of 9.4 μM. SP11 binds only to activated Fis1 by engaging Cys41. SP11 preserves mitochondrial integrity and function during oxidative stress, inhibits hydrogen peroxide-induced mitochondrial ROS production, mitochondrial fragmentation, and Drp1 mitochondrial translocation. SP11 can be used for the research of parkinson’s disease [1].
Cat. No.: HY-RS04951
Target:
Research Areas:
FIS1 Human Pre-designed siRNA Set A contains three designed siRNAs for FIS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19331
Target:
Research Areas:
Fis1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fis1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25822
Target:
Research Areas:
Fis1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fis1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70941
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Fis1; Mitochondrial Fission Molecule; Prev. TTC11; Fis1 Homolog; H_NH0132A01.6; HFis1; CGI-135; Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae); Tetratricopeptide Repeat Protein 11; Fission 1 (Mitochondrial Outer Membrane) Homolog (Yeast)
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
