5 Results for "

G361

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "G361" in MCE Product Catalog:

Cat. No.: HY-124113
CAS No.: 1224713-90-9
Purity:  99.94%
Synonyms: 4′‐BR
4'-Bromo-resveratrol (4′‐BR) is a dual SIRT1/SIRT3 inhibitor with an IC50 of 0.2 mM for both targets. 4'-Bromo-resveratrol induces caspase-dependent apoptosis, induces G0/G1 cell cycle arrest, and inhiibits proliferation. 4'-Bromo-resveratrol reduces lactate production, glucose uptake, and NAD +/NADH ratio, and downregulates lactate dehydrogenase A and glucose transporter 1 (GLUT1). 4'-Bromo-resveratrol can be used for the research of melanoma .
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Cat. No.: HY-162645
CAS No.: 3029897-97-7
Target:  

TAM Receptor

Research Areas:  

Inflammation/Immunology Cancer

BPR5K230 is a dual inhibitor for the receptor tyrosine kinase MER and AXL, with IC50 of 4.1 nM and 9.2 nM. BPR5K230 inhibits the proliferation of Ba/F3-MER with IC50 of 5 nM. BPR5K230 exhibits good pharmacokinetic characteristics in mice, exhibits anti-inflammatory and antitumor against 4T1, MDA-MB-231, MC38 and Hepa1?6 in mouse models .
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Cat. No.: HY-162825
Target:  

Photosensitizer

Research Areas:  

Cancer

Antitumor photosensitizer-7 (compound 15) is a photosensitizer with anti-cancer activity. Antitumor photosensitizer-7 exhibits significant cytotoxicity against the G361 melanoma cell line under 414 nm blue light irradiation .
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Cat. No.: HY-N16734
CAS No.: 85051-41-8
Norviburtinal is a non-selective cytotoxic and pro-angiogenic agent. Norviburtinal has an IC50 of 3.25 μg/mL on G361 melanoma cells and an effective concentration of 50 μg/mL on zebrafish embryos. Norviburtinal promotes capillary sprout formation in zebrafish subintestinal vessels (SIV) and has both cytotoxic and pro-angiogenic activities. Norviburtinal can be used in research on promoting angiogenesis related to melanoma, lung cancer, and wound healing .
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Cat. No.: HY-147520
CAS No.: 2408317-70-2
Target:  

FAK Apoptosis Autophagy

Research Areas:  

Cancer

FAK-IN-5 (Compound 8l) is a FAK signaling inhibitor. FAK-IN-5 induces cell apoptosis and autophagy .
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