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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
GRC-17536
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "GRC-17536" in MCE Product Catalog:
Cat. No.: HY-187618
CAS No.: 1649479-05-9
Target:
Research Areas:
GRC-17536 is a TRPA1 antagonist with selective inhibition of TRPA1-mediated calcium influx [4].GRC-17536 binds to TRPA1 binding site 2 to inhibit channel activity [3].GRC-17536 reduces irritant-induced cough responses and citric acid-induced cough responses [4].GRC-17536 exhibits antitussive activity [4].GRC-17536 has poor pharmacokinetic and bioavailability properties, leading to discontinued development after a Phase IIa study [2].GRC-17536 can be used for the research of painful diabetic polyneuropathy, peripheral diabetic neuropathy, asthma, and chronic cough .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
