1 Result for "

GSK 1264

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "GSK 1264" in MCE Product Catalog:

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Cat. No.: HY-182277
CAS No.: 1392118-63-6
Target:  

HIV Integrase HIV

Research Areas:  

Infection

GSK-1264 is an HIV-1 integrase inhibitor. GSK-1264 binds to a site spanning the HIV-1 integrase catalytic core domain and C-terminal domain, mediates formation of an open polymer of HIV-1 integrase dimers via inhibitor-bridged contacts between adjacent dimers. GSK-1264 disrupts late-stage HIV replication by interfering with viral particle assembly. GSK-1264 stimulates inappropriate polymerization of HIV-1 integrase. GSK-1264 can be used for the research of HIV infection .
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