1 Result for "

GSK180

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GSK180" in MCE Product Catalog:

  • Targets Recommended:
2
2 Cited Publications
Cat. No.: HY-112179
CAS No.: 1799725-26-0
Purity:  99.04%
Target:  

KMO

Research Areas:  

Inflammation/Immunology

GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. GSK180 rapidly changes levels of kynurenine pathway metabolites, and acts as a useful tool to probe the therapeutic potential of KMO inhibition .
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