12 Results for "

Geranylgeranyl pyrophosphate

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Geranylgeranyl pyrophosphate" in MCE Product Catalog:

Cat. No.: HY-126370
CAS No.: 6699-20-3
Geranylgeranyl pyrophosphate is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc .
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1 Cited Publications
Cat. No.: HY-113037C
CAS No.: 116057-57-9
Purity:  ≥95.0%
Synonyms: Farnesyl diphosphate ammonium
Farnesyl pyrophosphate (Farnesyl diphosphate) ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases .
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Cat. No.: HY-126370A
CAS No.: 313263-08-0
Purity:  ≥95.0%
Geranylgeranyl pyrophosphate triammonium is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate triammonium is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate triammonium regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc .
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Cat. No.: HY-113037
CAS No.: 13058-04-3
Synonyms: (E/Z)-Farnesyl diphosphate
(E/Z)-Farnesyl pyrophosphate ((E/Z)-Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. (E/Z)-Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. (E/Z)-Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .
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Cat. No.: HY-113037CS
Synonyms: Farnesyl diphosphate-d2 triammonium
Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is a deuterium labeled Farnesyl pyrophosphate triammonium (HY-113037C). Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.
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Cat. No.: HY-113037B
CAS No.: 372-97-4
Synonyms: Farnesyl diphosphate
Farnesyl pyrophosphate is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.
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Cat. No.: HY-144128
CAS No.: 1429012-38-3
Target:  

Apoptosis

Research Areas:  

Cancer

hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo .
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Cat. No.: HY-144129
CAS No.: 2241547-82-8
Target:  

Apoptosis

Research Areas:  

Cancer

hGGPPS-IN-2 (Compound 16g) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-2 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-2 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo .
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Cat. No.: HY-144130
CAS No.: 2763223-96-5
Target:  

Apoptosis

Research Areas:  

Cancer

hGGPPS-IN-3 (Compound 13h) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-3 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-3 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo .
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Cat. No.: HY-P70224
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GGPS1; GGPPS1; Geranylgeranyl Diphosphate Synthase 1; Geranylgeranyl Diphosphate Synthase; Geranylgeranyl pyrophosphate Synthase; GGPP Synthase; (2E,6E)-Farnesyl Diphosphate Synthase; GGPPSase; Dimethylallyltranstransferase; MUDHLOV; Farnesyl Diphosphate
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P702577
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GGPS1; GGPPS1; Geranylgeranyl Diphosphate Synthase 1; Geranylgeranyl Diphosphate Synthase; Geranylgeranyl pyrophosphate Synthase; GGPP Synthase; (2E,6E)-Farnesyl Diphosphate Synthase; GGPPSase; Dimethylallyltranstransferase; MUDHLOV; Farnesyl Diphosphate
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-N19747
CAS No.: 87501-14-2
Clerocidin dimer is a dimeric clerodane derivative antibiotic that can be found in fermentations of the fungus Oidiodendron truncatum. Clerocidin dimer exhibits antibiotic activity .
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