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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
Gi-biased signalling
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "Gi-biased signalling" in MCE Product Catalog:
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Forschungsgebiete:
AZ1729 is an FFA2/FFAR2 allosteric modulator and Gi-biased signaling enhancer. AZ1729 binds to the FFA2 allosteric site without interacting with the orthosteric site, enhances Gi coupling, and inhibits Gq/G11 coupling. AZ1729 inhibits Isoprenaline (HY-B0468)-induced lipolysis in mouse adipocytes. AZ1729 also induces human neutrophil migration. AZ1729 can be used to study the signaling pathways underlying the physiological roles of FFA2 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
