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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
HCV genotypes 5a
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "HCV genotypes 5a" in MCE Product Catalog:
11
Elbasvir (MK-8742) is a hepatitis C virus nonstructural protein 5A (HCV NS5A) inhibitor with EC50s of 4, 3 and 3 nM against genotype 1a, 1b, and 2a, respectively.
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Research Areas:
Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 2.16 μM .
Synonyms: Emitasvir diphosphate; DAG-181 diphosphate
Yimitasvir diphosphate (Emitasvir diphosphate; DAG-181 diphosphate) is an orally active inhibitor of hepatitis C virus (HCV) nonstructural protein 5A (NS5A). Yimitasvir diphosphate is applicable to research related to HCV infection .
Cat. No.: HY-12530R
CAS No.: 1377049-84-7
Synonyms: GS-5816 (Standard)
Target:
Research Areas:
Velpatasvir (Standard) is the analytical standard of Velpatasvir. This product is intended for research and analytical applications. Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 2.16 μM .
Cat. No.: HY-147358A
CAS No.: 1959593-23-7
Synonyms: Emitasvir; DAG-181
Yimitasvir (Emitasvir; DAG-181) is an orally active inhibitor of hepatitis C virus (HCV) nonstructural protein 5A (NS5A). Yimitasvir is applicable to research related to HCV infection .
Cat. No.: HY-15789R
CAS No.: 1370468-36-2
Synonyms: MK-8742 (Standard)
Target:
Research Areas:
Elbasvir (Standard) is the analytical standard of Elbasvir. This product is intended for research and analytical applications. Elbasvir (MK-8742) is a hepatitis C virus nonstructural protein 5A (HCV NS5A) inhibitor with EC50s of 4, 3 and 3 nM against genotype 1a, 1b, and 2a, respectively.
Cat. No.: HY-12530S1
Synonyms: GS-5816-d33
Cat. No.: HY-131905S
CAS No.: 1606150-08-6
Cat. No.: HY-125182
CAS No.: 2649904-85-6
Target:
Research Areas:
SMCypI C31 is a non-peptidic cyclophilin inhibitor with potent peptidyl-prolyl cis/trans isomerases (PPIase) inhibitory activity (IC50 of 0.1 µM). SMCypI C31 shows pangenotype anti-HCV activity with EC50s ranging from 1.20 to 7.76 μM for genotype 1a, 1b, 2a, 3a, and 5a HCV subgenomic replicons (HCV-SGRs) and chimeric genotype 2a/4a HCV-SGRs. SMCypI C31 disrupts the cyclophilin A-NS5A interaction .
Cat. No.: HY-W749691
Synonyms: (S)-GS-5816-13C,d3
Cat. No.: HY-12530S3
Synonyms: GS-5816-13C,d3
Cat. No.: HY-184880
CAS No.: 1410114-25-8
Target:
Research Areas:
BMS-986144 non-deuterated is the non-tritium form of BMS-986144 (HY-131905S). BMS-986144 non-deuterated is an orally active inhibitor of HCV NS3/4A protease. BMS-986144 non-deuterated binds to the active site of HCV NS3/4A protease and induces conformational changes in the protease. BMS-986144 non-deuterated reduces time-dependent CYP3A4 inhibition, exhibits hepatic microsomal metabolic stability, and undergoes oxidation of the macrocyclic linker chain. BMS-986144 non-deuterated can be used in studies related to hepatitis C virus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
