4 Results for "

HMCL

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HMCL" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-18621
CAS No.: 1338540-63-8
Target:  

TOPK Apoptosis

Research Areas:  

Cancer

OTS514 is a highly potent TOPK inhibitor with an IC50 of 2.6 nM. OTS514 strongly suppresses the growth of TOPK-positive cancer cells . OTS514 induces cell cycle arrest and apoptosis .
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Cat. No.: HY-169381
Target:  

Bcl-2 Family

Research Areas:  

Others

hMcl-1-IN-1 (Compound 9) is an hMcl-1 inhibitor based on His224 aryl sulfonate fluoride, with an IC50 value of 5.8 nM .
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Cat. No.: HY-18621A
CAS No.: 2319647-76-0
Target:  

TOPK Apoptosis

Research Areas:  

Cancer

OTS514 hydrochloride is a highly potent TOPK inhibitor, which inhibits TOPK kinase activity with a median inhibitory concentration (IC50) value of 2.6 nM. OTS514 hydrochloride strongly suppresses the growth of TOPK-positive cancer cells . OTS514 hydrochloride induces cell cycle arrest and apoptosis .
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Cat. No.: HY-P10386
Target:  

Bcl-2 Family

Research Areas:  

Cancer

155H1 (Compound 11) is a stapled peptide, that covalently binds hMcl1 (172-323) with IC50 of 18 nM .
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