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Results for "

IGF2BP1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Recombinant Proteins

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-144873
    AVJ16

    		Insulin Receptor Apoptosis Cancer
    AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 with a good affinity of Kd of 1.4μM. AVJ16 interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation .
    AVJ16
  • HY-156110
    IGF2BP1-IN-1

    		Insulin Receptor Cancer
    IGF2BP1-IN-1 (Compound A11) is a IGF2BP1 inhibitor and inhibits downstream signaling. IGF2BP1-IN-1 binds to IGF2BP1 protein with a KD value of 2.88 nM. IGF2BP1-IN-1 inhibits cancer cells proliferation (IC50: 9 nM for A549 cell, 34 nM for HCT116). IGF2BP1-IN-1 induces cancer cell apoptosis. GF2BP1-IN-1 inhibits tumor growth in A549 xenograft mouse model .
    IGF2BP1-IN-1
  • HY-124447
    BTYNB

    		IGF-1R c-Myc Apoptosis TGF-beta/Smad Cancer
    BTYNB is a structure-specific nucleic acid binder and IGF2BP1 inhibitor (with an IC50 of 5 μM against hBTYNB). BTYNB disrupts the IGF2BP1-RNA interaction and blocks its binding to oncogenic mRNAs such as c-Myc, MDM2, PD-L1. BTYNB completely blocks the INHBA-Smad2/3 pathway, disrupts the MYCN/IGF2BP1 loop, and thereby induces apoptosis and cell cycle arrest, effectively inhibiting the proliferation and survival of cancer cells. In addition, BTYNB acts as an immune activator and tumor microenvironment modulator, enhances T cell-mediated tumor killing, and produces significant synergistic effects with inhibitors of PD-1, BRD and BIRC5. BTYNB can be used in relevant research on various malignant tumors including ovarian cancer, neuroblastoma, leukemia and melanoma .
    BTYNB
  • HY-RS06619
    IGF2BP1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    IGF2BP1 Human Pre-designed siRNA Set A contains three designed siRNAs for IGF2BP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    IGF2BP1 Human Pre-designed siRNA Set A
    IGF2BP1 Human Pre-designed siRNA Set A
  • HY-RS23290
    Igf2bp1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Igf2bp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Igf2bp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Igf2bp1 Rat Pre-designed siRNA Set A
    Igf2bp1 Rat Pre-designed siRNA Set A
  • HY-RS16849
    Igf2bp1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Igf2bp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Igf2bp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Igf2bp1 Mouse Pre-designed siRNA Set A
    Igf2bp1 Mouse Pre-designed siRNA Set A

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