38 Results for "

IL-13 antibody

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "IL-13 antibody" in MCE Product Catalog:

Cat. No.: HY-P811263
Synonyms: NC30, IL13, Interleukin-13, IL-13

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human

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2
2 Cited Publications
Cat. No.: HY-P99053
CAS No.: 1044515-88-9
Synonyms: CAT354
Tralokinumab (CAT354) is a humanized IgG4 monoclonal antibody that specifically binds to and neutralizes IL-13. Tralokinumab can be used in the research of diseases such as asthma, atopic dermatitis, and pulmonary fibrosis .
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1
1 Cited Publications
Cat. No.: HY-P99496
CAS No.: 2151032-62-9
Synonyms: RPC 4046; ABT 308; CC-93538

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC50s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) .
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1
1 Cited Publications
Cat. No.: HY-P990121

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse IL-4 Antibody (11B11) is an anti-mouse IL-4 IgG1 monoclonal antibody. Anti-Mouse IL-4 Antibody (11B11) can inhibit Th2 cell differentiation by blocking the IL-4 signaling pathway. Anti-Mouse IL-4 Antibody (11B11) can significantly reduce fibrosis combined with anti-IL13 mAb. Anti-Mouse IL-4 Antibody (11B11) can be used for researches on cancer and inflammation conditions such as colorectal cancer and prostatitis .
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Cat. No.: HY-126360
CAS No.: 15646-46-5
Purity:  ≥98.0%
Research Areas:  

Inflammation/Immunology

Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins .
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Cat. No.: HY-P990093
CAS No.: 2734715-10-5
Synonyms: CM310

Research Areas:  

Inflammation/Immunology

Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα (KD values of 0.25 nM, 1.50 nM, and 2.75 nM for human, cynomolgus monkey, and rat IL-4Rα, respectively). Stapokibart effectively blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit IL-4Rα. Stapokibart reduces IL-4 and IL-13 mRNA, inhibits CD23 upregulation, and inhibits IL-4 and IL-13-induced STAT6 activation. Stapokibart improves inflammation (airway inflammation, rhinitis, dermatitis) .
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Cat. No.: HY-P991162
CAS No.: 2981469-90-1
Synonyms: PF-07275315
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Tilrekimig (PF-07275315) is a monoclonal antibody targeting human interleukin-4 (IL-4), interleukin-13 (IL-13) and thymic stromal lymphopoietin (TSLP). Tilrekimig can be used in the research of allergic and inflammatory diseases, such as asthma and atopic dermatitis .
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Cat. No.: HY-P990735
CAS No.: 2765066-99-5
Synonyms: UCB-1381

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Donzakimig is a trispecific anti-IL-13/IL-22/HSA antibody. Donzakimig adopts a Fab-scFv-scFv structural format (without an Fc region), in which the Fab domain is linked to the scFv domains via a S (G4S)2 linker. Donzakimig binds to and inhibits the activities of IL-13 and IL-22, thereby blocking the signal transduction of these two cytokines. Donzakimig can extend its serum half-life by binding to human serum albumin, enhancing its in vivo stability and achieving long-acting efficacy. Donzakimig can be used in research on moderate-to-severe atopic dermatitis, moderate-to-severe asthma (especially eosinophilic type), psoriasis, inflammatory bowel disease, and other conditions .
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Cat. No.: HY-P991266

Research Areas:  

Inflammation/Immunology

SM-17 is a human monoclonal antibody targeting IL-17RB. SM-17 binds to human IL-17RB, inhibits the dimerization of IL-17RA/IL-17RB, blocks IL-25-induced phosphorylation of ERK1/2 and STAT5, and suppresses Th2-mediated inflammatory responses. SM-17 inhibits the secretion of IL-5, IL-9, IL-13 and IL-4, impairs the proliferation/expansion of ILC2 and Th2 cells, and restores filaggrin expression. SM-17 reduces immune cell infiltration, epidermal hyperplasia, goblet cell hyperplasia, collagen deposition, ear swelling and scratching behavior in animal models. SM-17 can be used in research related to atopic dermatitis and allergic asthma .
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Cat. No.: HY-P990741
CAS No.: 2648456-30-6
Synonyms: UCB-9741

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Galvokimig is an anti-IL13/IL17A/ALB/IL17B monoclonal antibody .
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Cat. No.: HY-P99439
CAS No.: 910649-32-0
Synonyms: IMA-638

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anrukinzumab (IMA-638) is a humanized anti-IL-13 monoclonal antibody. Anrukinzumab effectively reduces lung inflammation in a cynomolgus monkey model. Anrukinzumab can be used in studies of ulcerative colitis (UC) as well as asthma .
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Cat. No.: HY-P990699
CAS No.: 2641479-65-2
Synonyms: ZTS-00008183

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Riltovetbart is a canine-derived IgG2 κ monoclonal antibody raised against Canlupfam IL13 .
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Cat. No.: HY-P99883
CAS No.: 1399584-78-1
Synonyms: SAR156597
Romilkimab (SAR156597) is a humanized IG antibody that specifically targets IL-4 and IL-13. Romilkimab can be used for the research of diffuse cutaneous systemic sclerosis .
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Cat. No.: HY-P99870
CAS No.: 2445460-16-0
Synonyms: ASLAN004; CSL-334; MK-6105

Target:  

Interleukin Related

Research Areas:  

Others

Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells .
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Cat. No.: HY-P99417
CAS No.: 2043952-59-4
Synonyms: UCB4144; VR 942

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Abrezekimab (UCB4144; VR 942) is a humanized, high-affinity, neutralizing anti-human-IL-13 antibody fragment that binds to IL-13. Abrezekimab prevents IL-13 binding to the IL-13 Rα1 subunit. Abrezekimab can be used for the research of asthma .
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Cat. No.: HY-P990090
CAS No.: 2648260-80-2
Synonyms: CBP-201

Research Areas:  

Inflammation/Immunology

Rademikibart (CBP-201) is a human monoclonal antibody targeting IL-4Rα and IL-4Rα inhibitor with a KD of 20.7 pM when binding to human IL-4Rα epitopes . Rademikibart does not bind to IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation and thymus activation regulated chemokine (TRAC) production. Rademikibart can be used for the research of atopic dermatitis and asthma .
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Cat. No.: HY-P991150
CAS No.: 2981477-39-6

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ompekimig is an immunoglobulin monoclonal antibody that targets IL-4, IL-13, IL-33. Ompekimig shows potential for use in immune-mediated inflammatory diseases such as asthma and atopic dermatitis .
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Cat. No.: HY-P991258

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

CNTO-5825 is a humanized monoclonal antibody inhibitor targeting interleukin-13 (IL-13). CNTO-5825 is promising for research of Th2-type inflammatory related diseases such as asthma and atopic dermatitis .
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Cat. No.: HY-P991633

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

TQC2938 is a humanized IgG2 monoclonal antibody inhibitor targeting Stimulation-2 (ST2). TQC2938 inhibits the ST2/IL-33 signaling pathway, reduces the level of downstream Th2 cytokines (such as IL-4, IL-5, and IL-13) and eosinophils as well as other inflammatory cells. TQC2938 can be used for inflammatory diseases like asthma research .
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Cat. No.: HY-P99846
CAS No.: 1528523-94-5
Synonyms: QAX576
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Dectrekumab (QAX576) is a human monoclonal antibody that targets IL-13. Dectrekumab significantly improves intraepithelial esophageal eosinophil counts and dysregulated esophageal disease-related transcripts with Eosinophilic esophagitis (EoE) in a sustained manner and can be used for inflammation and immunology related research .
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