2 Results for "

JR141

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "JR141" in MCE Product Catalog:

Cat. No.: HY-P991047
Synonyms: JR-141 antibody (uncoupled from iduronate 2-sulfatase)

Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease Cancer

Anti-CD71/TfR1 Antibody (JR-141 antibody (uncoupled from iduronate 2-sulfatase)) is a humanized anti-human transferrin receptor (CD71/TfR1) antibody. Anti-CD71/TfR1 Antibody is the antibody part of the fusion protein Pabinafusp alfa (HY-P99797). The recommend isotype control of Anti-CD71/TfR1 Antibody: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P99797
CAS No.: 2140211-48-7
Synonyms: JR-141

Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease

Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .
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