2 Results for "

KP4

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "KP4" in MCE Product Catalog:

Cat. No.: HY-W342082
CAS No.: 516-15-4
Synonyms: 11KP4
Research Areas:  

Cancer

11-Ketoprogesterone (11KP4) is the substrate for CYP17A1 and 11β-HSD2 that could be metabolized to 21-deoxycortisone (21dE) and 21-deoxycortisol (21dF) with glucocorticoid activity .
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Cat. No.: HY-182400
CAS No.: 2201065-84-9
Research Areas:  

Cancer

AGI-25696 is an orally active ethionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 97 nM. AGI-25696 reduces intracellular SAM levels in cancer cells. AGI-25696 inhibits tumor growth in mice bearing subcutaneous KP4 MTAP-null pancreatic xenografts. AGI-25696 can be used for the research of mtap-deleted pancreatic cancer .
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