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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
L-type amino acid transporter 1
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "L-type amino acid transporter 1" in MCE Product Catalog:
Cat. No.: HY-120139A
CAS No.: 2994330-89-9
(R)-KMH-233 is the isomer of KMH-233 (HY-120139), and can be used as an experimental control. KMH-233, a potent, reversible and selective l-type amino acid transporter 1 (LAT1) inhibitor, inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM) .
Cat. No.: HY-W267524
CAS No.: 14464-68-7
Target:
Research Areas:
H-Phe (3-CF3)-OH is a phenylalanine derivative targeting the L-type amino acid transporter 1 (LAT1, SLC7A5) as its core target, and it belongs to LAT1 substrates. H-Phe (3-CF3)-OH can be used for prodrug scaffold development and research related to multiple solid tumors .
Cat. No.: HY-W246010
CAS No.: 6278-96-2
Synonyms: Dibenzylglycine
Target:
Research Areas:
α,α-DiBn-DL-Gly (Dibenzylglycine) is an achiral α-substituted phenylalanine derivative, non-substrate weak inhibitor of LAT1 (L-type amino acid transporter 1). α,α-DiBn-DL-Gly does not stimulate efflux of-Gabapentin from preloaded HEK-hLAT1 cells. α,α-DiBn-DL-Gly shows minimal inhibition of-Gabapentin (HY-A0057) uptake into HEK-hLAT1 cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
