2. Search Result
Search Result
Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

LPS-stimulated macrophage cells

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

5

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0577
    Apiin
    1 Publications Verification

    Apigenin 7-O-apiosylglucoside; Apigenin 7-(2-O-apiosylglucoside)

    		 NO Synthase Inflammation/Immunology
    Apiin is a flavonoid glycoside-based iNOS inhibitor. Apiin inhibits the expression of inducible nitric oxide synthase in activated macrophages. Apiin exhibits anti-inflammatory activity .
    Apiin
  • HY-N7697F
    Chitobiose

    		Others Metabolic Disease
    Chitobiose is an orally active chitosan oligosaccharide (degree of polymerization 2). Chitobiose shows hepatoprotective activity and counteracts CCl4-induced elevation of plasma aspartate transaminase and alanine transaminase activities in rats. Chitobiose can be used for the research of carbon tetrachloride-induced acute hepatotoxicity .
    Chitobiose
  • HY-N1912
    Andropanolide

    		Others Cancer
    Andropanolide is a natural product that exerts cytotoxicity toward carcinoma cells and significantly inhibits the overproduction of nitric oxide (NO) in Lipopolysaccharides (HY-D1056) (LPS)-stimulated RAW264.7 macrophages .
    Andropanolide
  • HY-W573700
    Methyl everninate

    		Others Others
    Methyl everninate is the major constituent of the deuterochloroform. Methyl everninate, rhodomollosides A and B are the derivatives of Methyl everninate, with cytotoxicity against RAW264.7 cells. Both of they shows inhibitory effects with a lipopolysaccharide (LPS)-stimulated murine macrophages RAW 264.7 cells model .
    Methyl everninate
  • HY-N1117
    Tristin

    		Phosphatase NO Synthase Infection Metabolic Disease Cancer
    Tristin is a PTP1B inhibitor (IC50=21.2 μM) with antioxidant and antifungal activities. Tristin inhibits lipid peroxidation and NO production in LPS-stimulated macrophages, and also exhibits activity against a variety of phytopathogenic fungi. Tristin is also able to inhibit cancer cell proliferation. Tristin can be used in the research of diseases associated with phytopathogenic fungal infection, leukemia, type 2 diabetes and inflammatory responses .
    Tristin
  • HY-130743
    Dieugenol

    Bis-eugenol; Dehydrodieugenol

    		 Parasite Infection
    Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
    Dieugenol
  • HY-163368
    HDAC6-IN-34

    		HDAC Inflammation/Immunology
    HDAC6-IN-34 (compound 21) is an oral active and selective HDAC6 inhibitor with the IC50 of 18 nM. HDAC6-IN-34 increases the acetylation level of tubulin without affecting histone acetylation in cutaneous T-cell lymphoma cells and inhibits TNF-α secretion in LPS (HY-D1056)-stimulated macrophage cells. HDAC6-IN-34 shows excellent anti-arthritic efficacy in rat .
    HDAC6-IN-34

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: