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HDAC6-IN-34

HDAC6-IN-34 (compound 21) is an oral active and selective HDAC6 inhibitor with the IC50 of 18 nM. HDAC6-IN-34 increases the acetylation level of tubulin without affecting histone acetylation in cutaneous T-cell lymphoma cells and inhibits TNF-α secretion in LPS (HY-D1056)-stimulated macrophage cells. HDAC6-IN-34 shows excellent anti-arthritic efficacy in rat.

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  • CAS No.: 1432508-73-0
  • Formula: C18H18F3N3O3
  • Molecular Weight:381.35
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • HDAC6-IN-34 Chemical Structure
    HDAC6-IN-34 Chemical Structure
CAS No.: 1432508-73-0
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All HDAC Isoforms

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  • HDAC6-IN-34 Chemical Structure
    HDAC6-IN-34 Chemical Structure
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  • HDAC6-IN-34