139101-67-0
Chemical Structure
Tristin
- CAS. Nr.: 139101-67-0
- Formula:C15H16O4
- Molecular Weight:260.29
IUPAC Name: 5-(4-hydroxy-3-methoxyphenethyl)benzene-1,3-diol
InChIKey: KPFFMALTIRFAHW-UHFFFAOYSA-N
SMILES: OC1=CC(CCC2=CC=C(O)C(OC)=C2)=CC(O)=C1
Biological Activity: Tristin is a PTP1B inhibitor (IC50=21.2 μM) with antioxidant and antifungal activities. Tristin inhibits lipid peroxidation and NO production in LPS-stimulated macrophages, and also exhibits activity against a variety of phytopathogenic fungi. Tristin is also able to inhibit cancer cell proliferation. Tristin can be used in the research of diseases associated with phytopathogenic fungal infection, leukemia, type 2 diabetes and inflammatory responses[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tristin | 99.26% | Tristin is a PTP1B inhibitor (IC50=21.2 μM) with antioxidant and antifungal activities. Tristin inhibits lipid peroxidation and NO production in LPS-stimulated macrophages, and also exhibits activity against a variety of phytopathogenic fungi. Tristin is also able to inhibit cancer cell proliferation. Tristin can be used in the research of diseases associated with phytopathogenic fungal infection, leukemia, type 2 diabetes and inflammatory responses. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. ONO M, et al. Antioxidative constituents from Dendrobii Herba (stems of Dendrobium spp.)[J]. Food Science and Technology International, Tokyo, 1995, 1(2): 115-120.
- [2]. Zhou XM, et al. Bioactive Phenanthrene and Bibenzyl Derivatives from the Stems of Dendrobium nobile. J Nat Prod. 2016;79(7):1791-1797. [Content Brief]
- [3]. He L, et al. Recent research progress on natural small molecule bibenzyls and its derivatives in Dendrobium species. Eur J Med Chem. 2020;204:112530. [Content Brief]
