26544-34-3
Chemical Structure
Apiin
Synonym(s): Apigenin 7-O-apiosylglucoside;Apigenin 7-(2-O-apiosylglucoside)
- CAS No.: 26544-34-3
- Formula:C26H28O14
- Molecular Weight:564.49
IUPAC Name: 7-(((2S,3R,4S,5S,6R)-3-(((2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
InChIKey: NTDLXWMIWOECHG-YRCFQSNFSA-N
SMILES: O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO)[C@@H](O)[C@@H]3O)[C@@H]3O[C@@](OC[C@]4(O)CO)([H])[C@@H]4O)=C5)C2=C5O
Biological Activity: Apiin is a flavonoid glycoside-based iNOS inhibitor. Apiin inhibits the expression of inducible nitric oxide synthase in activated macrophages. Apiin exhibits anti-inflammatory activity[1].
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Apiin | 99.94% | Apiin is a flavonoid glycoside-based iNOS inhibitor. Apiin inhibits the expression of inducible nitric oxide synthase in activated macrophages. Apiin exhibits anti-inflammatory activity. | ||||||||||||||||||||
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Apiin (Standard) | ≥98% | Apiin (Standard) is the analytical standard of Apiin. This product is intended for research and analytical applications. Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells. | ||||||||||||||||||||
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Keywords
