19 Results for "

LRRC15

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "LRRC15" in MCE Product Catalog:

Cat. No.: HY-P99899
CAS No.: 2052591-32-7
Synonyms: PR-1498487

Target:  

ADC Antibodies

Research Areas:  

Cancer

Samrotamab (PR-1498487) is a humanized IgG1-κ chimeric monoclonal antibody targeting LRRC15, with a Kd of 5.42 nM for human LRRC15. Samrotamab disrupts the LRRC15-SCG5 signaling module by binding to a membrane-proximal conformational epitope within the C-terminal leucine-rich repeat region of LRRC15, which locates at the lateral edge of the LRR solenoid while fully exposing the canonical concave β-sheet surface. Samrotamab reduces the viability of bladder cancer cells, inhibits clonogenic growth, impairs cell migration and compromises cell invasion. Samrotamab induces compensatory upregulation of LRRC15 transcripts while suppressing the expression of SCG5 mRNA. Samrotamab is applicable to research on urothelial carcinoma, sarcoma, osteosarcoma and undifferentiated pleomorphic sarcoma .
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Cat. No.: HY-RS07808
Research Areas:  

Others

LRRC15 Human Pre-designed siRNA Set A contains three designed siRNAs for LRRC15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17927
Research Areas:  

Others

Lrrc15 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lrrc15 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24397
Research Areas:  

Others

Lrrc15 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lrrc15 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P701020
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIB; LRRC15
Species:  
Source:  
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Cat. No.: HY-P78486
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LIB; LRRC15
Species:  
Source:  
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Cat. No.: HY-P705057
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIB; LRRC15
Species:  
Source:  
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Cat. No.: HY-P705284
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIB; LRRC15
Species:  
Rat
Source:  
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Cat. No.: HY-P78172
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LIB; LRRC15
Species:  
Source:  
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Cat. No.: HY-P704768
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIB; LRRC15; EGM_11224
Source:  
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Cat. No.: HY-P700892
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIB; LRRC15; EGM_11224
Source:  
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Cat. No.: HY-P72512
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Leucine-rich repeat-containing protein 15; hLib; LRRC15; LIB
Species:  
Source:  
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Cat. No.: HY-P78695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Leucine-rich repeat-containing protein 15; LRRC15; LIB; hLib
Species:  
Source:  
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Cat. No.: HY-P76480
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Leucine-rich repeat-containing protein 15; hLib; LRRC15; LIB
Species:  
Source:  
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Cat. No.: HY-P78844
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Leucine-rich repeat-containing protein 15; LRRC15; LIB; hLib
Species:  
Source:  
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Cat. No.: HY-P78845
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Leucine-rich repeat-containing protein 15; LRRC15; LIB; hLib
Source:  
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Cat. No.: HY-P705181
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Leucine-rich repeat-containing protein 15; LRRC15; LIB; hLib
Source:  
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Cat. No.: HY-P83437
Synonyms: LIB

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P83437A
Synonyms: LIB

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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