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Results for "

LRRC4B

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS07821

    Small Interfering RNA (siRNA) Others

    LRRC4B Human Pre-designed siRNA Set A contains three designed siRNAs for LRRC4B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    LRRC4B Human Pre-designed siRNA Set A
    LRRC4B Human Pre-designed siRNA Set A
  • HY-P992426

    Tau Protein Neurological Disease
    NS101 is an anti-FAM19A5 antibody with an IC50 of 0.2 nM and a Kd of 111 pM, as well as blood-brain barrier permeability. NS101 binds to key amino acid residues of FAM19A5, thereby blocking the interaction of LRRC4B and disrupting the FAM19A5-LRRC4B complex. NS101 increases the dendritic spine density in hippocampal neurons and the prefrontal cortex, normalizes the dendritic spine elimination rate, elevates the frequencies of mEPSC and fEPSP, and promotes the transport of brain-derived FAM19A5 into the peripheral circulation. NS101 improves cognitive function in mouse models of Alzheimer's disease. NS101 can be used for research on Alzheimer's disease. The recommended isotype control is human IgG1 kappa (HY-P99001) .
    NS101

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