4 Results for "

LT3

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "LT3" in MCE Product Catalog:

Cat. No.: HY-176735
Target:  

IRAK FLT3 Apoptosis

Research Areas:  

Cancer

FLT3/IRAK4-IN-1 is a selective FLT3/IRAK4 inhibitor with the remarkable activity towards FLT3-WT (IC50 = 1.95 nM), FLT3-D835Y (IC50 = 3.22 nM) and IRAK4 (IC50 = 53.72 nM). LT3/IRAK4-IN-1 has relatively low toxicity to normal bone marrow cells, can effectively promote cell apoptosis, and has the potential to overcome drug resistance. FLT3/IRAK4-IN-1 can be used for research on acute myeloid leukemia (AML) .
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Cat. No.: HY-161709
CAS No.: 2452019-67-7
Research Areas:  

Cancer

FLT3/CDKs ligand-1 (Compound 14) is a ligand for target protein, which promotes the degradation of cyclin-dependent kinase (CDK) and the FMS-like tyrosine kinase 3 (FLT3), inhibits FLT3/CDK related proliferations and survivals of leukemia cells. LT3/CDKs ligand-1 can be used for synthesis of PROTAC FLT3/CDKs degrader-1 (HY-161708) .
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Cat. No.: HY-120436
CAS No.: 113785-48-1
Target:  

Drug Derivative

Research Areas:  

Cancer

RM 49 is the derivative of Mitomycin C (HY-13316). RM 49 exhibits cytotoxicity in SCLC and NSCLC lung cancer cells with IC50 of 0.01-0.5 μg/mL. RM 49 exhibits high relative antitumor activity in compared with Mitomycin C, Cisplatin (HY-17394), Carboplatin (HY-17393) and Doxorubicin (HY-15142) .
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Cat. No.: HY-P704240
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FLJ18683; LT3E; LTCRE; LCD3E; LCD3-epsilon
Species:  
Source:  
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