FLT3/CDKs ligand-1
FLT3/CDKs ligand-1 (Compound 14) is a ligand for target protein, which promotes the degradation of cyclin-dependent kinase (CDK) and the FMS-like tyrosine kinase 3 (FLT3), inhibits FLT3/CDK related proliferations and survivals of leukemia cells. LT3/CDKs ligand-1 can be used for synthesis of PROTAC FLT3/CDKs degrader-1 (HY-161708).
For research use only. We do not sell to patients.
- CAS No.: 2452019-67-7
- Formula: C26H31N9O3
- Molecular Weight:517.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK2 |
CDK4 |
CDK6 |
CDK9 |
Chemical Information
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CAS No. 2452019-67-7
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Molecular Weight 517.58
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Formula C26H31N9O3
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SMILES
O=C(C1=NNC=C1NC2=C3C(NC=C3)=NC=N2)NC4=CC=C(CN5CCN(C(OC(C)(C)C)=O)CC5)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)