FLT3/CDKs ligand-1
FLT3/CDKs ligand-1 (Compound 14) is a ligand for target protein, which promotes the degradation of cyclin-dependent kinase (CDK) and the FMS-like tyrosine kinase 3 (FLT3), inhibits FLT3/CDK related proliferations and survivals of leukemia cells. LT3/CDKs ligand-1 can be used for synthesis of PROTAC FLT3/CDKs degrader-1 (HY-161708).
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- CAS No.: 2452019-67-7
- Formule: C26H31N9O3
- Masse moléculaire:517.58
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Help & FAQs
Activité biologique
Description
IC50 & Target
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CDK2 |
CDK4 |
CDK6 |
CDK9 |
Chemical Information
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CAS No. 2452019-67-7
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Masse moléculaire 517.58
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Formule C26H31N9O3
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SMILES
O=C(C1=NNC=C1NC2=C3C(NC=C3)=NC=N2)NC4=CC=C(CN5CCN(C(OC(C)(C)C)=O)CC5)C=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FLT3/CDKs ligand-1 Related Classifications
HY-161709 Related Classifications
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