1 Result for "

M 3541

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "M 3541" in MCE Product Catalog:

Cat. No.: HY-160096
CAS No.: 1360628-91-6
Research Areas:  

Cancer

M3541 is an orally effective DNA-dependent protein kinase (DNA-PK) inhibitor . M3541 inhibits ionizing radiation-induced ATM autophosphorylation and phosphorylation of downstream substrates (KAP1, CHK2, p53), blocks DSB end resection and homologous recombination repair, and simultaneously induces non-homologous end joining, G2-M phase arrest, polyploidization, and cell death. M3541 can be used for research on solid tumors, acute myeloid leukemia, non-small cell lung cancer, triple-negative breast cancer, etc. .
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