34 Results for "

MAPK8

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "MAPK8" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N2593
CAS No.: 32507-66-7
Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes .
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4
4 Cited Publications
Cat. No.: HY-P80728
Synonyms: AI849689 antibody; c Jun N terminal kinase 1 antibody; C-JUN kinase 1 antibody; c-Jun N-terminal kinase 1 antibody; EC 2.7.11.24 antibody; JNK 1 antibody; JNK antibody; JNK-46 antibody; JNK1A2 antibody; JNK21B1/2 antibody; MAP kinase 8 antibody; MAPK 8 antibody; MAPK8 antibody; Mitogen activated protein kinase 8 antibody; MK08_HUMAN antibody; p54 gamma antibody; Prkm8 antibody; Protein kinase JNK1 antibody; Protein kinase, mitogen-activated, 8 antibody; SAPK 1 antibody; SAPK gamma antibody; SAPK1 antibody; Stress-activated protein kinase 1 antibody

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat, Hamster

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1
1 Cited Publications
Cat. No.: HY-P73848
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Mitogen-activated protein kinase 8; MAPK 8; JNK-46; JNK1; PRKM8
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P80830
Synonyms: JNK 46; JNK 55; MAPK10; MAPK9; MAPK8; SAPK1b; SAPK1; SAPK; PRKM10; PRKM9; PRKM8

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-128448
CAS No.: 3567-69-9
Purity:  ≥98.0%
Synonyms: Azorubine; Acid Red 14; E122
Carmoisine (Azorubine) is an azo dye that can be used as a food additive .
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Cat. No.: HY-148061
CAS No.: 2769753-53-7
Purity:  99.28%
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity .
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Cat. No.: HY-RS08121
Research Areas:  

Others

MAPK8 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-148063
CAS No.: 2769753-47-9
Purity:  98.80%
DB0614 is a PROTAC based on Cereblon ligand, which is a selective and potent targeted protein degrader of NEK9 inhibitor. DB0614 can degrade ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2 and ULK1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity .(Blue: Thalidomide-4-OH (HY-103596), Black: linker, Pink: FLT3-IN-17 (HY-148070))
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Cat. No.: HY-RS08123
Research Areas:  

Others

Mapk8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mapk8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08122
Research Areas:  

Others

Mapk8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mapk8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-128448R
CAS No.: 3567-69-9
Synonyms: Azorubine (Standard); Acid Red 14 (Standard); E122 (Standard)
Carmoisine (Standard) is the analytical standard of Carmoisine. This product is intended for research and analytical applications. Carmoisine (Azorubine) is an azo dye that can be used as a food additive .
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Cat. No.: HY-P705421
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP kinase 8; MAPK 8; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK8
Species:  
Source:  
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Cat. No.: HY-N20729
CAS No.: 99633-12-2
Eucommin A is a natural polyphenolic antioxidant. Eucommin A forms stable complexes with EGFR and MAPK8 via hydrogen bonding and hydrophobic interactions, and regulates osteoarthritis-related Autophagy. Eucommin A is applicable to research related to oxidative stress, such as osteoarthritis .
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Cat. No.: HY-RS08124
Research Areas:  

Others

MAPK8IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK8IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08125
Research Areas:  

Others

MAPK8IP2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK8IP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08126
Research Areas:  

Others

MAPK8IP3 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK8IP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS28583
Research Areas:  

Others

Mapk8ip1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mapk8ip1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-N2593R
CAS No.: 32507-66-7
Isorhapontigenin (Standard) is the analytical standard of Isorhapontigenin (HY-N2593). This product is intended for research and analytical applications. Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes.
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Cat. No.: HY-P86251
Synonyms: MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-RS22065
Research Areas:  

Others

Mapk8ip1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mapk8ip1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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