2 Results for "

MB3

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MB3" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-129039
CAS No.: 778649-18-6
Purity:  99.58%
Synonyms: MB-3
Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM). Butyrolactone 3 can be used in studies of cancer, metabolic, autoimmune and neurological diseases [3].
loading...
    loading...
Cat. No.: HY-149710
CAS No.: 1144114-27-1
Target:  

ICMT ERK

Research Areas:  

Cancer

POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation .
loading...
    loading...