1 Result for "

MD69276

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MD69276" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-14196
CAS No.: 29218-27-7
Purity:  98.11%
Synonyms: MD 69276
Target:  

Monoamine Oxidase

Research Areas:  

Neurological Disease

Toloxatone (MD 69276) is a reversible, selective MAO-A inhibitor that can cross the blood-brain barrier. Toloxatone increases the levels of serotonin (5-HT) and norepinephrine in the brain. Toloxatone reduces the immobility time in the forced swimming test in mice, inhibits killing behavior in rats without causing sedation, and shows a correlation between its free plasma concentration and cerebrospinal fluid concentration. Toloxatone is widely used in research related to depression, depressive disorders and Parkinson's disease .
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