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Results for "

MEC-1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
Products

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6744
    Chaetoglobosin A

    		Apoptosis Endogenous Metabolite Fungal Parasite Arp2/3 Complex Infection Cancer
    Chaetoglobosin A is a secondary metabolite and nematicide. Chaetoglobosin A is produced by Penicillium aquamarinium. Chaetoglobosin A targets Filamentous actin in cells, thereby inducing cell cycle arrest, and inhibiting membrane ruffle formation and cell migration. Chaetoglobosin A preferentially induces Apoptosis in chronic lymphocytic leukemia cells. Chaetoglobosin A induces dose- and time-dependent death in J2 larvae of the southern root-knot nematode (Meloidogyne incognita). Chaetoglobosin A can be used in studies related to root-knot nematode disease and chronic lymphocytic leukemia [1] .
    Chaetoglobosin A
  • HY-174865
    MMH-165-26

    		Ligands for Target Protein for PROTAC NF-κB Apoptosis Cancer
    MMH-165-26 is a ligand for RelA/p65. MMH-165-26 reduces the expression of RelA/p65 and has significant cytotoxicity in MEC-1 (LC50 = 0.37 μM) cells. MMH-165-26 can be used for synthesizing PROTACs such as JP-163-16 (HY-174864) [1].
    MMH-165-26
  • HY-RS01245
    ATR Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ATR Human Pre-designed siRNA Set A contains three designed siRNAs for ATR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ATR Human Pre-designed siRNA Set A
    ATR Human Pre-designed siRNA Set A
  • HY-163538
    TYM-3-98

    		PI3K Apoptosis Cancer
    TYM-3-98 is a selective inhibitor for PI3Kδ, with an IC50 of 7.1 nM. TYM-3-98 inhibits proliferationso of B-lymphoma cells. TYM-3-98 inhibits PI3K/AKT/mTOR signaling pathway through induction of apoptosis. TYM-3-98 exhibits good pahrmacokinetic characters and antitumor efficacy in mouse/rat model, without significant toxicity [1].
    TYM-3-98

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