1 Result for "

ML353

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML353" in MCE Product Catalog:

Cat. No.: HY-124984
CAS No.: 2990506-75-5
Purity:  98.07%
Target:  

mGluR

Research Areas:  

Neurological Disease

ML353 is a selective ligand of mGlu5 silent allosteric modulator (SAM) with an Ki value of 18.2 nM. ML353 improves the affinity of common allosteric sites, 20-fold higher than the previous mGlu5 SAM tool compound 5mpep. ML353 has potential applications in solving the intrinsic activity of SAM in vivo or as a agent blocker . ML353 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...