2 Results for "

MRTX 1257

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MRTX 1257" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-114436
CAS No.: 2206736-04-9
Purity:  98.04%
Target:  

Ras

Research Areas:  

Cancer

MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells .
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Cat. No.: HY-114436S
CAS No.: 2639608-44-7
MRTX-1257-d6 is the deuterium labeled MRTX-1257 (HY-114436). MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells .
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