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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
Mercaptopurine
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "Mercaptopurine" in MCE Product Catalog:
21
21 Publications Verification
Synonyms: Mercaptopurine; 6-MP
21
21 Publications Verification
Synonyms: Mercaptopurine hydrate; 6-MP hydrate
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6-Mercaptopurine hydrate (Mercaptopurine hydrate; 6-MP hydrate) is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.
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Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis .
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6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction .
Synonyms: Mercaptopurine-13C2,15N; 6-MP-13C2,15N
Cat. No.: HY-13677AR
CAS No.: 6112-76-1
Synonyms: Mercaptopurine hydrate (Standard); 6-MP hydrate (Standard)
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6-Mercaptopurine hydrate (Standard) is the analytical standard of 6-Mercaptopurine hydrate. This product is intended for research and analytical applications. 6-Mercaptopurine hydrate (Mercaptopurine hydrate; 6-MP hydrate) is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.
Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Cat. No.: HY-167710
CAS No.: 941185-83-7
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CRCD2 is a small molecule NT5C2 nucleotidase inhibitor with enhanced 6-mercaptopurine cytotoxic activity. CRCD2 can effectively reverse 6-mercaptopurine resistance caused by mutations in the NT5C2 gene or non-genetic activation mechanisms. CRCD2 combined with 6-mercaptopurine can enhance its cytotoxic activity in NT5C2 wild-type leukemia, showing its potential in the treatment of acute lymphoblastic leukemia .
Cat. No.: HY-105723A
CAS No.: 2839447-07-1
Synonyms: Duazomycin A sodium
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Duazomycin (Duazomycin A) sodium is a glutamine antagonist. Duazomycin sodium can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) (HY-13677) in experimental allergic encephalomyelitis (EAE) without increasing toxicity .
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Azathioprine (Standard) is the analytical standard of Azathioprine. This product is intended for research and analytical applications. Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis .
Cat. No.: HY-13677S
CAS No.: 82677-93-8
Synonyms: Mercaptopurine-d2; 6-MP-d2
Cat. No.: HY-P4397
CAS No.: 115499-13-3
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PU 23 is a non-carboxylic multidrug resistance protein 4 (MRP4) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine .
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Duazomycin A is a glutamine antagonist. Duazomycin A can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) (HY-13677) in experimental allergic encephalomyelitis (EAE) without increasing toxicity .
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Cat. No.: HY-W555991
CAS No.: 5856-48-4
Cat. No.: HY-P1162
CAS No.: 73168-24-8
Synonyms: SKF 100273
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7-Methyl-6-mercaptopurine (Compound 4) is a purine derivative and a substrate for thiopurine methyltransferase (TPMT) with Km and Vmax values of 231 μM and 2340 U/mg protein, respectively .
Cat. No.: HY-W654258
Cat. No.: HY-175390
Synonyms: TGDP sodium; 6-Thio-GDP sodium
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6-Thioguanosine-5'-O-diphosphate sodium (6-Thio-GDP sodium) (TGDP sodium) is an active metabolite of 6-Mercaptopurine (HY-13677). 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
