1 Result for "

Monardic acid A

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Monardic acid A" in MCE Product Catalog:

Monardic acid A
Monardic acid A
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Cat. No.: HY-N16715
CAS No.: 1607436-76-9
Category:  

Lignans Phenylpropanoids Plants Pulmonaria officinalis L. Boraginaceae

Target:  

Cholinesterase (ChE)

Monardic acid A is a selective inhibitor of AChE, with an IC50 of 53.1 μM against AChE from electric eel. Monardic acid A shows weak inhibitory activity against human erythrocyte AChE (IC50 >100 μM) and has no significant inhibitory effect on BChE. Monardic acid A reduces acetylcholine breakdown by inhibiting AChE activity, and also exhibits inhibitory activity against histamine release and hyaluronidase, thus exerting anti-inflammatory and neurotransmitter regulatory effects. Monardic acid A can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), and is mainly used in the development of anti-inflammatory drugs and drugs related to neurodegenerative diseases .
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