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5 Results for "
Monastrol
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Monastrol" in MCE Product Catalog:
11
11 Cited Publications
Synonyms: (±)-Monastrol
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM.
Cat. No.: HY-101071
CAS No.: 254753-54-3
Synonyms: (+)-Monastrol
(S)-Monastrol ((+)-Monastrol) is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cancer cell lines. (S)-Monastrol arrests mammalian cells in mitosis with monopolar spindles .
Cat. No.: HY-101071AR
CAS No.: 329689-23-8
Synonyms: (±)-Monastrol (Standard)
Target:
Research Areas:
Monastrol (Standard) is the analytical standard of Monastrol (HY-101071A). This product is intended for research and analytical applications. Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM.
Cat. No.: HY-117440
CAS No.: 1338701-15-7
4'-Methoxy-S-trityl-L-cysteinol is an allosteric inhibitor of vertebrate Kinesin Spindle Protein (KSP). 4'-Methoxy-S-trityl-L-cysteinol significantly enhances its inhibitory activity against NCI60 tumor cells by modifying the trityl and cysteine groups. Its EC50 for bipolar spindle formation is 28 μM, showing stronger inhibitory potency than the parent molecule and monastrol.
Cat. No.: HY-162518
Target:
Research Areas:
Eg5-IN-3 (5) is an Eg5 inhibitor that targets the novel allosteric pocket (α4/α6/L11). Eg5-IN-3 (5) causes tubulin assembly distortion with irregular morphology, resulting in a typical mitotic arrest similar to Monastrol (HY-101071A) .
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Protocols
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