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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
Multidrug resistance protein 1
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "Multidrug resistance protein 1" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P71140
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A4; Fibroblast-Specific protein-1; Prev. CAPL; Murine Placental Homolog; Prev. MTS1; protein S100-A4; PEL98; Metastasin 1; P9KA; protein Mts1; 18A2; Calvasculin; FSP1; Leukemia Multidrug resistance Associated protein; 42A; Malignant Transformation Sup
Species:
Human
Source:
E. coli
2
Target:
Research Areas:
Reversan (CBLC4H10) inhibits drug efflux mediated by P-glycoprotein (Pgp) and multidrug resistance protein 1 (MRP1), and exhibits oral activity. Reversan shows activity against glioblastoma multiforme and neuroblastoma models .
2
Target:
Research Areas:
Dofequidar (MS-209 free base) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect .
2
Target:
Research Areas:
Dofequidar fumarate (MS-209) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar fumarate has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect .
2
2
2 Cited Publications
Cat. No.: HY-P71084
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A4; Fibroblast-Specific protein-1; Prev. CAPL; Murine Placental Homolog; Prev. MTS1; protein S100-A4; PEL98; Metastasin 1; P9KA; protein Mts1; 18A2; Calvasculin; FSP1; Leukemia Multidrug resistance Associated protein; 42A; Malignant Transformation Sup
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P703175
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ABCB1; P-170; Prev. PGY1; ATP-Dependent Translocase ABCB1; Prev. MDR1; Phospholipid Transporter ABCB1; Prev. CLCS; Colchicin Sensitivity; Multidrug resistance protein 1; ATP-Binding Cassette Sub-Family B Member 1; ATP-Binding Cassette, Sub-Family B (MDR/T
Species:
Human
Source:
HEK293
Cat. No.: HY-P10856
CAS No.: 3085809-95-3
Target:
Research Areas:
Cat. No.: HY-162753
CAS No.: 2351940-23-1
Target:
Research Areas:
ZW-1226 is a dual Tyrosyl DNA phosphodiesterase 2 (TDP2) and Multidrug resistance-associated protein 1 (MRP1) inhibitor with IC50 values of 0.2 and 0.5 μM, respectively. ZW-1226 exhibits selectivity over other ABC transporters. ZW-1226 elevates intracellular GSH levels, and reverses MRP1-mediated drug resistance. ZW-1226 can be used for the research of leukemia, non-small-cell lung cancer, and multidrug resistant small-cell lung cancer .
Cat. No.: HY-10320G
CAS No.: 285983-48-4
Synonyms: BIRB 796 (GMP)
Doramapimod GMP (BIRB 796 GMP) is an orally active inhibitor for p38 MAPK, with IC50s of 38, 65, 200 and 520 nM, for p38α, p38β, p38γ, p38δ. Doramapimod exhibits cytotoxicity and antitumor activity against multiple myeloma, synergizes with multidrug resistance protein 1 (ABCB1) and aurora kinase inhibitor VX680, promoting their antitumor efficacy against oral epidermoid carcinoma and cervical cancer. Doramapimod also exhibits anti-inflammatory activity .
Cat. No.: HY-17013D
CAS No.: 158681-49-3
Synonyms: MS-209 sesquifumarate
Target:
Research Areas:
Dofequidar (MS-209) sesquifumarate is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar sesquifumarate has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar sesquifumarate competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect .
Cat. No.: HY-13574
CAS No.: 174254-13-8
Synonyms: VX 710-3
Target:
Research Areas:
Biricodar dicitrate (VX 710-3) is the dicitrate salt form of Biricodar (HY-13574A). Biricodar dicitrate is an inhibitor for P-glycoprotein and multidrug resistance-associated protein 1 (MRP-1), which increases the accumulation of chemotherapy drugs within cancer cells and shows effective chemosensitizing activity in multidrug resistant cells .
Cat. No.: HY-17013AR
CAS No.: 153653-30-6
Synonyms: MS-209 (Standard)
Target:
Research Areas:
Dofequidar (fumarate) (Standard) is the analytical standard of Dofequidar (fumarate). This product is intended for research and analytical applications. Dofequidar fumarate (MS-209) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar fumarate has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect .
Cat. No.: HY-P86662
Synonyms: ABC20; ABCB1; ATP binding cassette, sub family B(MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; PGY1.
Cat. No.: HY-P85934
Synonyms: ABC20; ABCB1; ATP binding cassette, sub family B; MDR/TAP; , member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1; PGY1
Cat. No.: HY-P86055
Synonyms: ABC20; ABCB1; ATP binding cassette, sub family B; MDR/TAP; , member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1; PGY1
Cat. No.: HY-P86336
Synonyms: ABC20; ABCB1; ATP binding cassette, sub family B; MDR/TAP; , member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1; PGY1
Cat. No.: HY-P80772A
Synonyms: p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243
Cat. No.: HY-P703174
Synonyms: ABCB1; P-170; Prev. PGY1; ATP-Dependent Translocase ABCB1; Prev. MDR1; Phospholipid Transporter ABCB1; Prev. CLCS; Colchicin Sensitivity; Multidrug resistance protein 1; ATP-Binding Cassette Sub-Family B Member 1; ATP-Binding Cassette, Sub-Family B (MDR/T
Species:
Human
Source:
HEK293
Cat. No.: HY-P71140A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A4; Fibroblast-Specific protein-1; Prev. CAPL; Murine Placental Homolog; Prev. MTS1; protein S100-A4; PEL98; Metastasin 1; P9KA; protein Mts1; 18A2; Calvasculin; FSP1; Leukemia Multidrug resistance Associated protein; 42A; Malignant Transformation Sup
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
