1 Result for "

NACHT-subdomain

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NACHT-subdomain" in MCE Product Catalog:

Cat. No.: HY-169996
CAS No.: 2557349-50-3
NP3-253 is an orally active and brain-penetranted NLRP3 inflammasome inhibitor. NP3-253 functions as a molecular glue that prevents NACHT-subdomain rearrangements, locking NLRP3 in an inactive conformation. NP3-253 inhibits production of pro-inflammatory cytokines IL-1β and IL-18. NP3-253 can be used for the research of inflammation and neurological disease, suah as peritonitis .
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