1 Result for "

NSC697923

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NSC697923" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-13811
CAS No.: 343351-67-7
Purity:  99.93%
Research Areas:  

Cancer

NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity .
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