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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
OMA1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "OMA1" in MCE Product Catalog:
Cat. No.: HY-RS16953
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Research Areas:
Oma1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Oma1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09781
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OMA1 Human Pre-designed siRNA Set A contains three designed siRNAs for OMA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23396
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Oma1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Oma1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P72010
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: 2010001O09Rik; DAB1; FLJ33782; Metalloendopeptidase OMA1; Metalloendopeptidase OMA1; mitochondrial; Metalloprotease-related protein 1; mitochondrial; MPRP 1; MPRP-1; MPRP1; OMA1; OMA1 homolog zinc metallopeptidase; OMA1 homolog; zinc metallopeptidase S. cerevisiae; ; OMA1 zinc metallopeptidase;
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Cat. No.: HY-180786
CAS No.: 3085711-53-8
Research Areas:
DdBIC is a pyroptosis inducer. DdBIC binds to Nur77 and triggers its translocation to mitochondria, activates SDHA to deplete succinyl-CoA, disrupts heme homeostasis, induces electron leakage, and elicits mitochondrial ROS production. DdBIC induces mitochondrial ROS that oxidatively activates OMA1, promotes OPA1 cleavage and its release into the cytoplasm, activates the integrated stress response via PERK, and ultimately activates granzyme B to cleave GSDMC. DdBIC can be used for the study of melanoma [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
