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Octoclothepine

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106587A
    Octoclothepin maleate salt

    Clorotepine maleate salt

    		 Drug Derivative 5-HT Receptor Neurological Disease
    Octoclothepine (Clorotepine) maleate salt, an analog of Clozapine (HY-14539), is a neuroleptic and antipsychotic agent. Octoclothepine maleate salt exists in enantiomeric forms, where the (+)-form acts as an atypical antipsychotic, while the (-)-functions as a typical antipsychotic. (+)-Octoclothepine maleate salt exhibits extremely high binding affinity for 5-HT₆ and 5-HT₇ receptors, with Ki values of 0.41 and 0.38 nM; the Ki values of (-)-Octoclothepine maleate salt are 17.7 and 1.3 nM, respectively. Octoclothepine maleate salt can be used in research related to schizophrenia .
    Octoclothepin maleate salt
  • HY-106587
    Octoclothepine

    Clorotepine

    		 5-HT Receptor Drug Derivative Neurological Disease
    Octoclothepine (Clorotepine), an analog of Clozapine (HY-14539), is a neuroleptic and antipsychotic agent. Octoclothepine exists in enantiomeric forms, where the (+)-form acts as an atypical antipsychotic, while the (-)-functions as a typical antipsychotic. (+)-Octoclothepine exhibits extremely high binding affinity for 5-HT₆ and 5-HT₇ receptors, with Ki values of 0.41 and 0.38 nM; the Ki values of (-)-Octoclothepine are 17.7 and 1.3 nM, respectively. Octoclothepine can be used in research related to schizophrenia .
    Octoclothepine

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