1 Result for "

P62-RNF168 agonist-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "P62-RNF168 agonist-1" in MCE Product Catalog:

Cat. No.: HY-151799
CAS No.: 2765180-17-2
Purity:  98.62%
Research Areas:  

Cancer

P62-RNF168 agonist-1 (compound 5a) is a low cytotoxicity P62-RNF168 agonist that enhances the interaction between P62 and RNF168. P62-RNF168 agonist-1 induces a reduction in H2A ubiquitination mediated by RNF168 and impairs homologous recombination-mediated DNA repair. P62-RNF168 agonist-1 also inhibits the growth of xenograft tumors in mice in a dose-dependent manner .
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