35 Results for "

PD II

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "PD II" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-10259A
CAS No.: 136676-91-0
Pureté:  99.34%
Target:  

Angiotensin Receptor

Domaines de recherche:  

Cardiovascular Disease Endocrinology

PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.
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4
4 Cited Publications
Cat. No.: HY-10581
CAS No.: 112811-59-3
Pureté:  99.69%
Synonyms: AM-1155; BMS-206584; PD135432
Domaines de recherche:  

Infection Neurological Disease Cancer

Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic that can cross the blood-brain barrier, with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50=0.109 μg/ml) . Gatifloxacin can be used to treat bacterial conjunctivitis in vivo.
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4
4 Cited Publications
Cat. No.: HY-10581A
CAS No.: 121577-32-0
Pureté:  99.89%
Synonyms: AM-1155 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride
Domaines de recherche:  

Infection

Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml) . Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
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1
1 Cited Publications
Cat. No.: HY-41121
CAS No.: 15761-38-3
Synonyms: Boc-Ala-OH
Domaines de recherche:  

Cancer

Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma .
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Cat. No.: HY-21623
CAS No.: 95464-05-4
Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct is a common dichloromethane solvate of the palladium catalyst Pd(dppf)Cl2, a phosphine ligand palladium(II) complex, which can be used as a versatile precatalyst for various cross-coupling reactions. Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct can stabilize reaction intermediates and lower the reaction activation energy in coupling reactions, and can be used in Suzuki-Miyaura coupling reaction studies .
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Cat. No.: HY-P99573
CAS No.: 2245725-04-4
Synonyms: MGD-013

Target:  

LAG-3

Domaines de recherche:  

Inflammation/Immunology Cancer

Tebotelimab (MGD-013) is a humanized IgG4κ bispecific PD-1/LAG-3 dual-affinity re-targeting (DART) antibody. Tebotelimab binds cell-surface expressed PD-1 and LAG-3 with EC50s of 1.65 nM and 0.41 nM in NS0 cells, respectively. Tebotelimab blocks PD-1/PD-L1, PD-1/PD-L2 and LAG-3/HLA (MHC-II) interactions and PD-1 signaling. Tebotelimab restores exhausted T-cell responses and and enhances antitumour immunity .
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Cat. No.: HY-W013066
CAS No.: 205319-10-4
Pd(Xantphos)Cl2 is a palladium(II) complex catalyst that can be used in organic synthesis research.
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Cat. No.: HY-121767
CAS No.: 114785-12-5
Target:  

Angiotensin Receptor

Domaines de recherche:  

Cardiovascular Disease

PD 123177 is a nonpeptide antagonist specific for angiotensin II (AII) subtype AT2 receptor in mammalian systems .
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Cat. No.: HY-P99922
CAS No.: 2173096-82-5

Target:  

LAG-3

Domaines de recherche:  

Cancer

Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft) .
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Cat. No.: HY-W033277
CAS No.: 21797-13-7
Synonyms: NSC 307191; Palladium(II) tetrafluoroborate tetraacetonitrile complex
Domaines de recherche:  

Others

Tetrakis(acetonitrile)palladium(II) tetrafluoroborate (NSC 307191) acts as a potent Lewis acid and facilitates the formation of the 2:1 complex [Pd(1,2-bis(2′-pyridylethynyl)benzene)2](BF4)2 through the Sonogashira cross-coupling reaction.
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Cat. No.: HY-10259
CAS No.: 130663-39-7
Synonyms: (S)-(+)-PD 123319
Target:  

Angiotensin Receptor

Domaines de recherche:  

Cardiovascular Disease Endocrinology

PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.
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Cat. No.: HY-P4569
CAS No.: 23827-93-2
Target:  

Dipeptidyl Peptidase

Domaines de recherche:  

Others

H-Ser-Pro-OH is a dipeptide containing serine and proline, which can serve as a substrate for prolinase I (PD I) and PD II. H-Ser-Pro-OH can also be used for the synthesis of polypeptide .
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Cat. No.: HY-P2470
CAS No.: 2135542-85-5
Target:  

PD-1/PD-L1

Domaines de recherche:  

Cancer

Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity .
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Cat. No.: HY-W127815
CAS No.: 40680-45-3
Pd(II) Mesoporphyrin IX is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-105453
CAS No.: 114785-18-1
Synonyms: WL 19
Target:  

Angiotensin Receptor

Domaines de recherche:  

Cardiovascular Disease

PD 121981 is a angiotensin II receptor antagonist. PD 121981 can be used for the research of cardiovascular disease .
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Cat. No.: HY-10581C
CAS No.: 180200-66-2
Synonyms: AM-1155 sesquihydrate; BMS-206584 sesquihydrate; PD135432 sesquihydrate
Domaines de recherche:  

Infection Inflammation/Immunology

Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml) . Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis in vivo.
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Cat. No.: HY-136417
CAS No.: 119654-64-7
Synonyms: PD(II) meso-tetraphenyltetrabenzoporphyrin
Pd(II)TPBP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W112936
CAS No.: 110314-07-3
Pd(II)TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-120857
CAS No.: 171179-37-6
Synonyms: PD 158294
Target:  

EGFR

Domaines de recherche:  

Others

BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50=8 pM). It is selective for EGFR over an assortment of other tyrosine and serine/threonine kinases. Cellular studies indicate that BPIQ-II can enter cells and very selectively shut down EGF-stimulated signal transmission by binding competitively at the ATP site of EGFR.
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Cat. No.: HY-144746
CAS No.: 2966090-78-6
Target:  

PD-1/PD-L1

Domaines de recherche:  

Cancer

PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases .
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