BPIQ-II hydrochloride
BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50=8 pM). It is selective for EGFR over an assortment of other tyrosine and serine/threonine kinases. Cellular studies indicate that BPIQ-II can enter cells and very selectively shut down EGF-stimulated signal transmission by binding competitively at the ATP site of EGFR.
For research use only. We do not sell to patients.
- CAS No.: 171179-37-6
- Formula: C15H11BrClN5
- Molecular Weight:376.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 171179-37-6
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Molecular Weight 376.64
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Formula C15H11BrClN5
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SMILES
BrC1=CC(NC2=NC=NC3=C2C=C4NC=NC4=C3)=CC=C1.Cl
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Synonyms
PD 158294
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BPIQ-II hydrochloride Related Classifications
HY-120857 Related Classifications
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