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Cat. No.: HY-105453

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PD 121981

(Synonyms: WL 19)

PD 121981 is a angiotensin II receptor antagonist. PD 121981 can be used for the research of cardiovascular disease.

For research use only. We do not sell to patients.

CAS No.: 114785-18-1
Formula: C₃₀H₂₉N₃O₄
Molecular Weight:495.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PD 121981 Chemical Structure

CAS No.: 114785-18-1

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PD 121981 is a angiotensin II receptor antagonist. PD 121981 can be used for the research of cardiovascular disease^[1].

All Angiotensin Receptor Isoforms :

In Vitro

PD 121981 antagonize AII inotropic responses with pA2 of 7.99 in isolated papillary muscles from rabbit heart^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 114785-18-1
Molecular Weight 495.57
Formula C₃₀H₂₉N₃O₄
SMILES

OC(C1N(C(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)CC(N=C4)=C(C1)N4CC5=CC(C)=C(OC)C=C5)=O
Synonyms

WL 19
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Scott AL, et al. Cardiac angiotensin receptors: effects of selective angiotensin II receptor antagonists, DUP 753 and PD 121981, in rabbit heart. J Pharmacol Exp Ther. 1992 Jun;261(3):931-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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PD 121981

All Angiotensin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PD 121981 Related Classifications

HY-105453 Related Classifications